The famous gulf between the arts and the sciences comes from the current pervasiveness of scientific illiteracy.The resultant increased fragmentation of science threatens scientific research; the resultant increase of the portion of the population of the advanced world that shows general ignorance of science threatens Western culture and democracy,
Unveiling the Capacity Drop Phenomenon Through Traffic Microsimulation: Modeling, Calibration, and Sensitivity Analysis
The Capacity Drop (CD) is a sustained drop in a freeway bottleneck outflow when its upstream section becomes congested.Understanding how to replicate CD with microscopic models can help us to better understand its properties and mechanism.However, there is no published study replicating an Kitchen Appliances observed occurrence of CD using microsco
Investigation of Oxygen Enriched air intake on diesel engine exhaust emissions
One of the methods to reduce the emissions in a diesel engine is by oxygen introduction into the combustion chamber which can be done by supplying the oxygen into the inlet manifold during suction stroke.Oxygen affects different parameters such as brake thermal efficiency, fuel consumption, NOx and smoke at different load conditions.Load test was c
Long span DNA paired-end-tag (DNA-PET) sequencing strategy for the interrogation of genomic structural mutations and fusion-point-guided reconstruction of amplicons.
Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements are a hallmark of cancer.While genomic DNA paired-end-tag (DNA-PET) sequencing is an attractive approach to identify genomic SVs, the current application of PET sequencing with short insert size DNA can be insufficient fo
Combination of oridonin and TRAIL induces apoptosis in uveal melanoma cells by upregulating DR5
AIM: To investigate the inhibitory effect of the combined use of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and oridonin on choroidal melanoma cell lines, and to explore its underlying mechanism.METHODS: MUM-2B and C918 cells were treated with different concentrations of TRAIL and oridonin, and MTT assay used to evaluate the in